Yes, sesame seeds are low histamine. They’re also a great source of magnesium, calcium, and iron, and their oil is wonderful for stir-frying all sorts of vegetables and meat. Many people enjoy them in the form of a sesame seed butter known as tahini, which is also a prominent ingredient in Middle Eastern cooking. All of these forms of sesame seeds are low histamine, but be wary of all the sesame-based candies you see floating around, as most of them are more sugar than seeds and contain all sorts of inflammatory flavorings & colorings. Sesame seeds are also high oxalate, which many people have a sensitivity to. If you’ve ever reacted to a nut or seed in the past, take caution when reintroducing sesame seeds.