Yes, pecans are low histamine. However, some people can still have a histamine reaction to pecans due to the presence of other biogenic amines, which compete with histamine to be cleared from your system. But if you’ve never had problems with other nuts or seeds, pecans would make a healthy addition to your diet. They’re a rich source of manganese and heart-healthy types of fat, and are a popular addition to desserts. Pecan flour actually makes for a moist and unique addition to your gluten-free flour blend.