Is Gluten Low Histamine?

Yes, gluten is (technically) low histamine. However, it’s recommended to avoid it in the first one to two months of a low histamine diet, as it can further irritate an inflamed stomach. In fact, recent research suggests that the increasingly common issue of non-celiac gluten sensitivity (NCGS) may even be due to undiagnosed histamine intolerance in patients.

This is because gluten is a plant-derived protein known to irritate the lining of the gut in certain individuals, causing inflammation and increasing intestinal permeability. So even if you feel sure that breads, pastas, cookies, and cakes aren’t causing your issues, there’s enough science-backed evidence to make it worth completely eliminating gluten during the first month of an elimination diet, just to be sure.

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